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Physiology Respiratory System Pa 1 a7f8af08

Pulmonary function changes seen in Emphysema are all except:

A
| TLC
B
| RV
C
| FEV1
D
| D V/D P
High-Yield Explanation
Emphysema Lung compliance is increased in emphysema. Destruction of the alveolar septa causes alveoli to coalesce and form large cavities. This increases their distensibility. Thus, (DV/DP) or compliance is increased. Due to early airway closure, air is trapped within the alveoli at the end of incomplete expiration. Hence, RV and TLC increase in emphysema. FEV1 is decreased in emphysema. It is a COPD in which, elastase released from alveolar macrophages destroys the elastin. Destruction of the pulmonary architecture results. There will be less mechanical tethering exeed on the conducting airways; thus airways more prone to collapse during expiration. Hence, FEV1 is reduced. Alveoli has tendency to collapse more easily than normal airways, the MEFR is greatly reduced Maximum expiratory flow volume (MEFV): When a person expires with great force, the expiratory airflow reaches a maximum flow beyond which the flow cannot be increased anymore, even with greatly increased additional force.

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