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Pharmacology C.N.S a7a33065

The following statements are true for the therapy with lithium except:

A
It is used in bipolar disorder
B
Amiloride is useful in treating lithium induced diabetes insipidus
C
Regular measurements of blood concentration of lithium is necessary
D
Sodium ion is a specific antidote for lithium clearance
High-Yield Explanation
Ans. (D) Sodium ion is an specific antidote for lithium clearance(Ref: KDT 8/e p476-477)There is no specific antidote for lithium.Lithium is the drug of choice for the treatment of bipolar disorder and prophylaxis of acute mania.It is a narrow therapeutic index drug and requires therapeutic drug monitoring.Amiloride is the drug of choice for lithium induced diabetes insipidus.
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