Full 2L QBank
Medicine General a7580720

A patient presents with thrombocytopenia, eczema and recurrent infections. What is the most probable diagnosis?

A
Wiskott Aldrich syndrome
B
A beta gammaglobulinemia
C
Chediak higashi syndrome
D
Lazy leukocyte syndrome
High-Yield Explanation
Wiskott-Aldrich syndrome (WAS) is an X-linked platelet/immunologic disorder caused by mutations in the WASP gene. The triad of eczema, recurrent infections, and microthrombocytopenia that characterizes WAS only occurs in 27% of the cases. The immunologic defects include low serum concentrations of IgM, while IgA and IgG are normal and IgE is frequently increased. Ref: The Elements of Immunology By Fahim Halim Khan, 2009, Page 413 ; Harrison's 17th ed chapter 310

Related Medicine MCQs

Practice 2,00,000+ NEET PG Questions Free

Timed mock tests, mistake queue analytics, audio lectures & zero attempt limits on i❤️Exams.

Start Free Mock Test Now