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Pharmacology Adverse Drug Effect a730ffd1

Ichthyoses is a side effect of -

A
Clofazamine
B
Cephalosporin
C
Capreomycin
D
Lctrozole
High-Yield Explanation
Ans. is 'a' i.e., Clofazamine Clofazimineo Clofazimine is a leprostatic drug.o It acts by interfering the template function of DNA.o Adverse effects of clofazimine1. Skin -Reddish-black discolouration of skin, dryness of skin and itching. Discolouration of hair and body secretions, acneform eruptions and phototoxicity, conjuctival pigmentation.2. GIT -Enteritis with loose stools, nausea, abdominal pain, anorexia and weight loss.Remember - Clofazimine has antiinflammatory property can be used in lepra reaction.

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