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Gynaecology & Obstetrics Sexuality and intersexuality a6ec1e26

Regarding androgen insensitivity syndrome, which statement is/are true:

A
Genotype is 46 XX
B
Scanty pubic hair
C
Well developed female external genitalia
D
Uterus absent
High-Yield Explanation
Androgen insensitivity syndrome (AIS) is an intersex condition that results in the paial or complete inability of the cell to respond to androgens. The unresponsiveness of the cell to the presence of androgenic hormones can impair or prevent the masculinization of male genitalia in the developing fetus, as well as the development of male secondary sexual characteristics at pubey, but does not significantly impair female genital or sexual development. As such, the insensitivity to androgens is clinically significant only when it occurs in genetic males (i.e. individuals with a Y-chromosome, or more specifically, an SRY gene).Clinical phenotypes in these individuals range from a normal male habitus with mild spermatogenic defect or reduced secondary terminal hair, to a full female habitus, despite the presence of a Y-chromosome.

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