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Pharmacology General a6b54aff

Antitubercular drug which is least hepatotoxic: September 2010

A
Rifampicin
B
Pyrazinamide
C
Ethambutol
D
INH
High-Yield Explanation
Ans. C: Ethambutol The single biggest problem with TB treatment is drug-induced hepatitis, which has a moality rate of around 5%. Three drugs can induce hepatitis: PZA, INH and RMP (in decreasing order of frequency). It is not possible to distinguish between these three causes based purely on signs and symptoms.

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