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Pharmacology Anticoagulants and Coagulants a6a089c8

A patient of thrombosis of veins has been receiving coumarin therapy for three years. Recently she developed bleeding tendency. How will you reverse the effect of coumarin therapy?

A
Protamine injection
B
Vit K injection
C
Infusion of fibrinogen
D
Whole blood transfusion
High-Yield Explanation
Ans. (B) Vit. K injection(Ref: KDT 8/e p661,662)Vitamin K is used to reverse bleeding tendency (raised INR) in warfarin overdose whereas fresh frozen plasma is treatment of choice for bleeding due to warfarin.

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