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Pharmacology Central Nervous system a68ba389

Which of the following abolishes the therapeutic effect of levodopa:

A
Thiamine
B
Carbidopa
C
Pyridoxine
D
Benserazide
High-Yield Explanation
Pyridoxine abolishes therapeutic effect of levodopa by enhancing peripheral decarboxylation of levodopa, less is available to cross to the brain. Ref KD Tripathi 8th ed.

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