The most common histological variant of renal cell carcinoma is:

Answer is A (Clear cell type) Clear cell carcinomas are the most common histological type of Renal cell carcinoma Carcinoma Type Frequency Place of origin Cell of origin Cytogenetics Growth Pattern Clear cell 60% Coex Proximal tubule 3p- Acinar or sarcomatoid Papillary 5-15% Coex Proximal tubule +7, +17, -Y Papillary or sarcomatoid Chromophobic 5-10% Coex Coical collecting duct Hypodiploid Solid, tubular. or sarcomatoid Oncocytic 5-10% Coex Coical collecting duct Undetermined Tumor nests Collecting duct < I% Medulla Medullary collecting duct Undetermined Papillary or sarcomatoid