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Medicine General a6287fdb

Acetaminophen poisoning causes which of the following changes in the liver?

A
Centrilobular necrosis in liver
B
Microvesicular fatty infiltration in hepatocytes
C
Cholestasis
D
Peripoal inflammation
High-Yield Explanation
Acetaminophen poisoning typically causes centrilobular necrosis in liver. Ref: Harrison's Principles of Internal Medicine, 18th Edition, Page 2560, see Table: 305-1.

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