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Pharmacology Other topics and Adverse effects a5ffd718

Regarding the antibacterial action of gentamicin, which of the following statements is most accurate?

A
Efficacy is directly propoionate to the time that the plasma level of the drug is greater than the minimal inhibitory concentration
B
Gentamicin continues to exe antibacterial effects even after plasma levels decrease below detectable range
C
Antibacterial activity is often reduced by the presence of an inhibitor of cell wall synthesis
D
The antibacterial action of gentamicin is time dependent
High-Yield Explanation
(Ref:Katzung 10/e p756, 757) Aminoglycosides show concentration dependenbt killing and prolonged post antibiotic effect. For details, refer to text.
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