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Microbiology Misc. a5ef7694

Fungus which cannot be grown on artificial media is?

A
Rhinosporidium seeberi
B
Penicillium marneffei
C
Aspergillus flavus
D
Sporothrix schenckii
High-Yield Explanation
ANSWER: (A) Rhinosporidium seeberiREF: Dail and Hammar's Pulmonary Pathology: Non-neoplastic Lung Disease 3rd edition, page 404, http: //www.cdc.gov/ncidod/eid/vol6no3/pdf/fredr icks .pdfThe etiologic agent of Rhinosporidiosis, Rhinosporidium seeberi, is an enigmatic microbe that has been difficult to classify. Recently, R. seeberi has been considered a fungus, but it was originally thought to be a protozoan parasite. R. seeberi has not been detected in the environment, and its natural host or reservoir is unknown. Attempts to propagate this organism on artificial media have failed, as has continuous co-cultivation with human cell lines."The fungus cannot be isolated on synthetic media of transmitted experimentally to animals; however, it will grow in cell culture"

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