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Pharmacology General a5c91825

Therapeutic uses of Prostaglandin El include all of the following except -

A
Medical termination of pregnancy
B
Impotence
C
Primary pulmonary hypeension
D
Maintenance of patent ductus aeriosus (PDA)
High-Yield Explanation
Ans. is 'c' i.e., Primary pulmonary hypeension o PGI2 is used for primary pulmonary hypeension (not PGE1). Impoant uses of PGs PGI2 (epoprostenal) o For extracorporeal circulation in dialysis and cardiopulmonary bypass o Primary pulmonary hypeension o To maintain the patency of ductus aeriosus (PDA) o For storage of platelets for transfusion PGE, (Alprastadil) To treat erectile dysfunction To maintain the PDA Misoprost - NSAIDS induced peptic ulcer o Misoprost For induction of labour in first few weeks ofpregnancy ---> medical termination ofpregnancy PGE2 (Dinoprostone) o Intravaginally for induction of midtrimester aboion o For cervical ripening a uveoscieduring labour

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