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Pathology Haematology a57f2bc5

A 9 year old boy with elevation in both PT and A PTT. What is the diagnosis? -

A
Defect in extrinsic pathway
B
Defect in intrinsic pathway
C
Platelet function defect
D
Defect in common pathway
High-Yield Explanation
APTT is used to measure the intrinsic system factors as well as factors common to both intrinsic and extrinsic system. PT measures extrinsic system factor as well as factors in common pathway. As both are affected defect is in common pathway. Reference : Harsh Mohan textbook of pathology, 7th edition.Pg no.307,308

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