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Medicine General a4f349fe

Medical treatment for gall bladder stone is amenable for :

A
Stones less than 15 mm in size
B
Radioopaque stone
C
Calcium bilirubinate oxalate stone
D
Nonfunctioning stones associated with gall bladder
High-Yield Explanation
Answer is A (Size of stone less than 15mm) Medical therapy for gall bladder stone is amenable for stones < 15 mm (preferably Prerequisites for medical therapy : Gall bladder should he functioning Stones should be radiolucent Size should be small preferably < 15 mm Q -Harrison 14'h (<10n/in-Harrison 16th) Stones should be 'cholesterol stones' only Obvious by thier mechanism of action)Q (Newer edition of Harrison has mentioned the size of stone to be preferably < 10 mm rather than < 15 mm but we will go with same answer because the question was framed in older times). Medical therapy for Gall stone dissolution consists of administration of : UDCA (Ursodeoxycholic acid)Q CDCA (Choledeoxycholic acid)Q Mechanism of action: Inhibit HMG-CoA reductase activityQ, which in turn results in decreased hepatic cholesterol synthesis. Allows dispersion of 'cholesterol' from stones by physicochemical means.

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