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Pharmacology General a42a0f95

Which of the following is the drug of choice for treatment of peptic ulcer disease ?

A
Omeprazole
B
Pirenzepine
C
Ranitidine
D
Sucralfate
High-Yield Explanation
Ans. is 'a' i.e., Omeprazole o PPI are the DOC for peptic ulcer (gastric or duodenal), GERD, ZE syndrome, prevention of aspiratory pneumonia and NSAID induced gastric / duodenal ulcers. Note - PGE1 analogue (Misoprostol) is specific drug for prevention and treatment of NSAID induced ulcer, but DOC is PPI.

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