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Pediatrics Liver and Biliary System a3efbaf6

Conj ugated hyperbilirubinemia -

A
Dubin Johnson syndrome
B
Criggler najjar syndrome
C
Breast mi lk jandice
D
Gilbert syndrome
High-Yield Explanation
Ans. is 'a' i.e., Dubin johnson syndrome o Breast milk jaundice-Decrease bilirubin uptake across hepathocyte membrane.Entero-hepatic recirculation.Leads to indirect hyperbilirubinemia.o Crigler najjar & Gilbert syndrome (deficiency of glucuronyl transferase) <Type I - Complete deficiency Type II - Partial deficiencyy Decrease conjugation leads to Indirect hyperbilirubinemia.Defect in hepatocyte secretion of conjugated bilirubin, a Leads to direct hyperbilirubinemia.

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