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Pathology G.I.T. a3eed6ab

Characteristic of Barrett's esophagus is?

A
Increased risk of SCC
B
Columnar Metaplasia
C
Most commonly in middle one third of esophagus
D
Gastric metaplasia is most common
High-Yield Explanation
Ans. is 'b' i.e. Columnar metaplasia * Barrett's esophagus is a metaplasia in which normal squamous epithelium of lower part of esophagus is replaced by columnar epithelium due to prolonged esophageal reflux.* Most common type of metaplasia in Barrett's esophagus is intestinal metaplasia which is characterized by presence of intestinal goblet cells in the metaplastic columnar epithelium.* Barrett's esophagus is a pre-malignant condition. It is the single most important risk factor for adenocarcinoma of esophagus.

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