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Pharmacology General a38adaa3

Wigabatrin' a new antiepileptic agent acts by ?

A
GABA- antagonis
B
GABA - agonism
C
NMDA antagonism
D
Carbonic anhydrase inhibition
High-Yield Explanation
Ans is 'b' i.e., GABA-agonism o Vigabatrin (y-vinyl GABA) is an inhibitor of GABA transaminase, the enzyme which degrades GABA. o Anticonvulsant action is due to increase synaptic GABA concentration.

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