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Pediatrics General a386966a

4 year old male child had febrile seizures, best prophylaxis -

A
Paracetamol 6 hourly
B
Paracetamol & diazepam
C
Diazepam
D
Phenobarbitone
High-Yield Explanation
Ans. is 'c' i.e., Diazepam Prophylaxis in febrile seizures Prophylactic anticonvulsants are not given routinely in febrile seizures. They are required when ? i) Febrile seizure is prolonged or complicated ii) Medical reassurance fails to relieve family anxiety. Prophylaxis may be continuous or intermittent Intermittent prophylaxis o It is currently the desirable form of therapy o It is used during episodes of fever o Indicated during first three days of fever. o Drugs that are used are - Diazepam and other benzodiazepenes (these drugs are used because they attain desired levels quickly) Diazepam is given oral or rectal. Continuous prophylaxis - o It is used when Intermittent therapy has failed Recurrent atypical seizures Central nervous system disease Family history of epilepsy o Drugs used are --> Sodium valproate or phenobarbitone. Note - Carbamazepine and phenytoin are ineffective for prevention of recurrence.

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