Pharmacology General pharmacology a3725f24

First order kinetics is characterized by:

Dose independent elimination

Decreasing clearance as plasma concentration increases

Increasing rate of elimination as plasma concentration increases

No relationship between rate of elimination and plasma concentration

High-Yield Explanation

First order (exponential) kinetics; The rate of elimination is directly propoional to the drug concentration, Clearance remains constant, or a constant fraction of the drug present in the body is eliminated in unit time. Ref:KD Tripathi pharmacology 7th edition (page.no: 30)

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