A 30 year old male, who met with a A, regained conscious after 36 hours. It was then discovered that the patient is unable to create new memories. The probable site of lesion for this symptom is

From the history, it is clear that the patient is suffering from anterograde amnesia. Therefore the site of lesion is hippocampus. Hippocampus is the primary structure within temporal lobe involved in conversion of sho-term memory to long-term memory. Hippocampal cognitive map is inappropriately reactivated during a deja vu experience. Hippocampus doesnot store memory but only conves sho-term memory to long-term memory. Hence, hippocampal lesions cause only anterograde amnesia. Ref: Ganong's Review of Medical Physiology 25th edition Pgno: 285, 288