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A 3 week old boy is brought to pediatrics emergency depament with projectile vomiting which is non bilious. On physical examination, firm, olive like mass is noted in the epigastric region post breastfeed and USG revealed thickened pyloric muscle. What is the most likely pathological finding if the pylorus muscle is biopsied?

A
<img style="max-width: 100%" src=" />
B
<img style="max-width: 100%" src=" />
C
<img style="max-width: 100%" src=" />
D
<img style="max-width: 100%" src=" />
High-Yield Explanation
The clinical symptoms, examination with USG findings of thickened pyloric muscle (>3mm) and elongated pyloric canal (>15mm) reveal the diagnosis as CHPS- congenital hyperophic pyloric stenosis which has hyperophy of circular muscle as depicted in option A Hyperophy-Small spindle-shaped (uterine smooth muscle cells) from a normal uterus, compared with large plump cells (the gravid uterus), at the same magnification.A Normal kidney tubules with Early (reversible) ischemic injury showing surface blebs, increased eosinophilia of cytoplasm, and swelling of few cells. Atrophy-Normal brain parenchyma of a young adult compared with Atrophy of the brain. Note made is of loss of brain substance that narrows the gyri and widens the sulci. Apoptosis- The shown cell is reduced in size, contains brightly eosinophilic cytoplasm and a condensed nucleus.

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