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Pharmacology General a27c2027

Which drug is excreted unchanged in urine ?

A
Verapamil
B
Furosemide
C
Propranolol
D
Thiopentone
High-Yield Explanation
Ans. is 'b' i.e., Furosemide Furosemide pharmacokinetics Furosemide is rapidly absorbed orally but bioavailability is about 60%. Lipid solubility is low and it is highly bound to plasma proteins. It is pay conjugated by glucuronic acid and is mainly excreted unchanged by glomerular filtration and tubular secretion.

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