To rule out rheumatoid arthritis, most important among the followings is?

DR4 is strongly associated with RA(also with Type 1 DM Pemphigus vulgaris). Other options HLA-B27 is associated with seronegative spondyloarthropathies (ankylosing spondylitis, Psoriatic arthritis, Reiter’s syndrome, reactive arthritis) and acute anterior uveitis HLA DR8 is associated with Type 1 DM. HLA DQ1 is associated with pemphigus vulgaris.