A child with fever presents with multiple tender erythematous skin lesions. On microscopic examination the skin lesions are seen to have neutrophilic infiltration in the dermis. What is the diagnosis?
High-Yield Explanation
Sweet's syndrome, (acute febrile neutrophilic dermatosis) although vasculitis type changes may be seen histologically. It is not a vascular disease. Intense neutrophilic inflammation of the skin is one of its most striking characteristic. Sweet's syndrome is also associated with inflammatory bowel disease and infections like chlamydia, streptococcus. Ref: Acute adult dermatology: Diagnosis and management, by Daniel Creamer, Jonathon Barker, Page 94.