Full 2L QBank
Biochemistry Metabolism of carbohydrate a252d123

Which of the following pathway occurs paly in mitochondria and paly in cytosol?

A
Glycolysis
B
Kreb's cycle
C
Ketogenesis
D
Urea cycle
High-Yield Explanation
In mammals, the urea cycle takes place primarily in the liver, and to a lesser extent in the kidney. The urea cycle consists of five reactions: two mitochondrial and three cytosolic. The cycle conves two amino groups, one from NH4+ and one from Asp, and a carbon atom from HCO3-, to the relatively nontoxic excretion product urea at the cost of four "high-energy" phosphate bonds (3 ATP hydrolyzed to 2 ADP and one AMP). Ornithine is the carrier of these carbon and nitrogen atoms.Ref: DM Vasudevan, 7th edition, page no: 196,203,226

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