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Surgery Miscellaneous (Neoplasia) a233bb28

In oesophageal ca which Neoadjuvant chemotherapy is used :

A
Cisplatin
B
Cyclophosphamide
C
Doxorubicin
D
Methotrexate
High-Yield Explanation
Ans. is 'a' ie Cisplatin Sabiston writes-" Since its introduction in 1980, cisplatin has emerged as the cornerstone of combination therapy in esophageal cancer. As a single agent, it has a response rate of 25% to 30%. Given in combination with 5- fluorouracil, a response rate of 50% may be achieved, and this is an established chemotherapeutic regimen for esophageal cancer. "

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