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Pharmacology Cardiovascular system a22f2bce

The following calcium channel blocker is specifically indicated to counteract cerebral vasospasm and neurological sequelae following subarachnoid haemorrhage

A
Lacidipine
B
Nicardipine
C
Nimodipine
D
Nitrendipine
High-Yield Explanation
Nimodipine It is a sho-acting DHP which penetrates blood-brain barrier very efficiently due to high lipid solubility. Uses:- It is believed to selectively relax cerebral vasculature and is approved for prevention and treatment of neurological deficit due to cerebral vasospasm following subarachnoid haemorrhage or ruptured congenital intracranial aneurysms. Side effects:- Headache, flushing, dizziness, palpitation and nausea. Ref:- kd tripathi; pg num:-550

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