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Microbiology General a1fa0704

(gd) T cell is associated with?

A
CD4
B
CD5
C
Cd8
D
First line defense against bacterial peptides
High-Yield Explanation
Ans. D-First line defense against bacterial peptides(gd) T cell: Gamma delta (gd) T cells have a TCR that is made up of one g (gamma) chain and one d (delta) chain.This group of T cells is usually much less common than ab T cells, but are at their highest abundance in the gut mucosa, within a population of lymphocytes known as intraepithelial lymphocytes (IELs).Constitute 5% of total cells, express y/6 chains of TCR chains; instead of ?/b chains.They lack both CD4 and CD8 molecules.They do not require antigen processing and MHC presentation of peptides.They lack both CD4 and CD8 molecules.They do not require antigen processing and MHC presentation of peptides.They are pa of innate immunity as the(gd) receptors exhibit limited diversity for the antigen.They are usually found in the gut mucosa, as intraepithelial lymphocytes (IELs).The function of (gd) T-cells is not known, they may encounter the lipid antigens that enter through the intestinal mucosa.

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