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Anatomy Other topics and Adverse effects a1d2fec8

Mrs Reeta Wardhan, a 50 year old female with rheumatoid ahritis is being considered for infliximab therapy. Which of the following test should be performed before beginning treatment

A
Liver function test
B
PPD skin test
C
Pulmonary function test
D
Visual examination
High-Yield Explanation
Ref-Katzung 11/e p633 Infliximab is a monoclonal antibody against TNF-0. It is commonly used to treat moderate to severe rheumatoid ahritis paicularly in patients .adverse effects, including reactivation of latent tuberculosis. All patients being considered for TNF-a inhibitor therapy should have a baseline PPD skin test to screen for latent tuberculosis..

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