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Medicine General a1b18367

Severe hepatotoxicity associated with steatohepatitis, most likely a result of mitochondrial toxicity, is being recognized with:

A
Zidovudine
B
Didanosine
C
Indinavir
D
All
High-Yield Explanation
Severe hepatotoxicity associated with steatohepatitis, most likely a result of mitochondrial toxicity, is being recognized with increasing frequency with antiretroviral therapy with reverse transcriptase inhibitors (e.g., zidovudine, didanosine) or protease inhibitors (e.g., indinavir, ritonavir. Reference: Harrisons Principles of Internal Medicine, 18th Edition, Page 2560

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