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Pediatrics Congenital CNS malformations a19db228

Neural tube defects have which one of the following inheritance patterns?

A
Autosomal dominant
B
Autosomal recessive
C
X-linked recessive
D
Multifactorial
High-Yield Explanation
- Neural tube defects: Occurs d/t failure of proper closure of neural tube Show multifactorial inheritance. Examples: 1. Meningocele 2. Meningomyelocele 3. Anencephaly 4. Spina bifida occulta 5. Iniencephaly 6. Encephalocele - Extra Edge: Other conditions having multifactorial inheritance are Hypeension Diabetes mellitus Most of the congenital hea diseases etc

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