Which toll-like receptors are involved in the action of bacterial endotoxins -

Different TLRs can recognize different antigens as listed below. TLR-1:- Bacterial lipoprotein and peptidoglycans TLR-2:- Bacterial peptidoglycans TLR-3:- Double-stranded RNA TLR-4:- Lipopolysaccharides TLR-5:- Bacterial TLR-6:- Bacterial lipoprotein TLR-7:- Single-stranded RNA, bacterial and viral TLR-8:- Single-stranded RNA, bacterial and viral, phagocytized bacterial RNA. TLR-9:- CpG DNA TLR-10:- Unknown TLR-11:-Profilin from Toxoplasma gondii, also possibly uropathogenic bacteria TLR-12:-Profilin from Toxoplasma gondii TLR-13:- bacterial ribosomal RNA Lipopolysaccharides (LPS), also known as lipoglycans and endotoxins, are large molecules consisting of a lipid and a polysaccharide composed of O-antigen, outer core and inner core joined by a covalent bond; they are found in the outer membrane of Gram-negative bacteria, and elicit strong immune responses in animals. The term lipooligosaccharide ("LOS") is used to refer to a low-molecular-weight form of bacterial lipopolysaccharides