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Pathology Immunology a189aa4b

Toll like receptors, recognize bacterial products and stimulates immune response by:

A
Perforin and granzyme mediated apoptosis
B
FADD ligand apoptosis
C
Transcription of nuclear factor mediated by NF-kB which recruits cytokines
D
Cyclin
High-Yield Explanation
Toll-like receptors They are membrane proteins that recognize a variety of microbe-derived molecules and stimulate innate immune responses against the microbes. These derive there name due to homology to a Drosophila protein called 'Toll'. The Toll-like receptors are expressed on many immune cells of the body. Signaling by Toll-like receptors results in the activation of transcription factors, notably NF-kB and AP-1.

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