Pharmacology General a122f50d All of the following are true about Irinotecan except A It is a Topo-isomerase II inhibitor B It is excreted though liver C It is used for colorectal cancer D It can cause diarrhoea because of cholinergic property High-Yield Explanation Irinotecan & Topotecan are Topoisomerase-I inhibitors. Etoposide & Teniposide are Topoisomerase-II inhibitors.