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Medicine General a0fa8e23

Tangier disease is characterised by which of the following lipid abnormalities?

A
Extremely low circulating level of plasma cholesterol
B
Low level of LDL but high HDL level
C
Extremely low level of triglycerides
D
Very high level of triglycerides
High-Yield Explanation
Tangier disease is a very rare autosomal dominant form of extremely low plasma HDL-Cholesterol caused by mutations in the gene encoding ABCA1. Ref: Harrisons Principles of Internal Medicine, 18th Edition, Page 3154

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