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Ophthalmology Uveal Tract a0f2b6f9

The Uveitis associated with vitiligo & auditory defects occurs in

A
Bechet's syndrome
B
Steven's Johnson syndrome
C
Vogt-Koyanagi syndrome
D
Ankylosing-spondylitis
High-Yield Explanation
Ans. is 'c' i.e Vogt Koyanagi Harada Syndrome * Vogt Koyanagi Harada Syndrome is a multisystem disorder characterized by Cutaneous lesionsOtological:VitiligoDeafnessAlopeciaTinnitusPoliosisVertigo Neurological lesionsOcular:Encephalopathy, MeningismusUveitisRetinal detachmentAssociated with HLA DR4 & DW15Bechet's Syndrome is characterized bv *Recurrent uveitisApthous ulcerationsGenital ulcerationsErythema multiformeAssociated with HLA B5 *Steven's Johnson Syndrome - is a cutaneous drug reaction.Clinical features include-Initial feature is always sore throat, malaise feverLesions involve 2 mucous memb. sites.Small blisters on dusky purpuric maculesTotal percent of body surface area blistering and eventual detachment is less than 10% (Note >=30% is seen in TEN, Toxic Epidermal Necrosis, the most serious cutaneous drug reaction)

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