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Pharmacology Targeted Anticancer Drugs and Immunosuppressants a08ac193

Sirolimus is more likely to cause ____________ more than cyclosporine:

A
Hypeension
B
Osteoporosis
C
Renal insufficiency
D
Thrombocytopenia
High-Yield Explanation
* Sirolimus (rapamycin) results in suppression of bone marrow,mainly causing thrombocytopenia.other adverse effects are diarrhoea,liver damage and pneumonitis. * Cyclosporine and tacrolimus cause nephrotoxicity,hepatotoxicity,neurotoxicity as an adverse effect.

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