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Pharmacology Anticoagulants and Coagulants a064454d

All of the following statements are true regarding warfarin toxicity (skin necrosis) except:

A
Skin necrosis occurs during initiation of therapy
B
Most common sites are toes and tips of fingers
C
Decreased quantity of protein C
D
Decreased incidence of adverse effects if therapy with LMWH is started.
High-Yield Explanation
Ans. (B) Most common sites are toes and tips of fingers(Ref: Harrison 18/e p433)Common sites of warfarin-induced skin necrosis are breasts, thighs and buttocks.

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