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Pharmacology General pharmacology a0100af2

Which of the following is not an Oxidative type of drug metabolism?

A
Deamination
B
N-oxidation
C
N-dealkylation
D
Glucuronidation
High-Yield Explanation
Oxidation; This reaction involves the addition of oxygen/negatively charged radical or removal of hydrogen/positively charged radical. oxidations-phase 1 metabolizing reactions Various oxidation reactions are hydroxylation; oxidation at C, N or S atoms; N or O-dealkylation, oxidative deamination, etc. Glucuronide conjugation is a synthetic reaction (phase 2 metabolic reactions) Ref: KD Tripathi pharmacology 7th edition (page.no: 24)

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