Germ cell tumour not common in young males-
High-Yield Explanation
(D) (Lymphoma) (1385-86, Baily and Love 26th, (953-CSTD 13th, 1326 S. Das 7th)* LYMPHOMA IS MORE COMMON IN ELDERLY PATIENTS -CLASSIFICATION OF TESTICULAR TUMOURS -A) Germ Cell Tumours (GCT)B) Non-Germ Cell Tumoursa) Seminoma (45%) (Most common)a) Interstial tumours 1.5% i) Leydig cell tumourii) Sertoli cell tumourb) Teratoma (38%)b) Lymphoma c) Other tumoursa) Teratoma differentiated (TD)b) Malignant teratoma, intermediate (MTI) (Terato carcinoma)c) Malignant teratoma, undifferentiated (MTU) (Embryonal carcinoma)d) Malignant teratoma trophoblastic (MTT) (Chorio-carcinoma).The peak incidence of teratoma is between 25 and 30 years of age and that for seminoma is between 35 and 45 years of age and combined tumours occupy in intermediate age group -* Most common testicular tumour in prepubertal adults is yolk sac tumour.Testicular tumours -* A solid testicular lump that cannot be felt separately from the testis may be a malignant tumour.* Painless firm mass within the testicle in a man age 18 to 40.* Lymphatic spread to the para-aortic lymph node**.* Ultrasound is a mandatory investigation in all cases of suspected testicular tumours.* Tumour markers AFP (Yolk sac tumour) HCG.(Choriocarcinoma) Lactic dehydrogenase should be measured prior to orchidectomy.Enlarged retroperitoneal nodes on abdominal CT scan).* Testicular tumours are extremely sensitive to platinum based chemotherapy.* Prognosis is excellent when patient is treated with combination chemotherapy BEP (Bleomycin, etoposide and cis-platinum) in a cancer centre.