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Medicine Infection 9fe971d3

Two students from a university dormitory building have contracted meningitis due to Neisseria meningitides. Which of the following students in the dormitory are most likely to benefit from chemoprophylaxis?

A
everybody in the dormitory, with oral amoxicillin
B
close contacts only, with oral amoxicillin
C
everybody in the dormitory, with oral rifampin
D
close contacts only, with oral rifampin
High-Yield Explanation
Although only close contacts need chemo-prophylaxis, it is sometimes given more widely than recommended because of community concern. Meningococcal vaccine is effective against serotype A and C, and will prevent late secondary infection in close contacts. Ciprofloxacin or ofloxacin are alternatives to rifampin.

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