Peripheral & central chemoreceptors may both contribute to increased ventilation that occurs as a result of decreased

The central chemoreceptors monitor the H+ concentration of cerebrospinal fluid (CSF), including the brain interstitial fluid.The receptors in the carotid and aoic bodies(peripheral chemoreceptors) are stimulated by a rise in the PCO2 or H+ concentration of aerial blood or a decline in its PO2.Ref: Ganong's Review of Medical Physiology, Twenty-Third Edition, Page number: 627, 628