Which of the following is false regarding TRALI?
High-Yield Explanation
Ref. Robbins Pathology. 9th edition. Page. 666
TRALI:
Transfusion-Related Acute Lung Injury (TRALI) is a syndrome characterized by acute respiratory distress following transfusion.
All plasma-containing blood products have been implicated including rare reports of IVIG and cryoprecipitate
It is a rare complication of allogeneic blood transfusion
Two theories on the pathogenesis of TRALI have been proposed
Antibodies to white blood cell antigens (HLA, granulocyte and monocyte)
Clinical condition of the patient (e.g. sepsis, trauma, etc) which causes sequestration of primed neutrophils in the activated pulmonary endothelium