A 34 year old housewife reports a three month history of feeling low, lack of interest in activities, lethargy, multiple body-aches, ideas of worthlessness, decreased appetite and disturbed sleep with early morning awakening. She is likely to benefit from -

This patient has (for 3 months) Depressed mood (feeling low)        Lack of interest     Loss of energy / fatigue (lethargy) Ideas of worthlessness Disturbed sleep (insomnia / hypersomnia)        Decreased appetite As more than 5 symptoms are present for more than 2 weeks, Diagnosis is major depression Antidepressant should be given.