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Pediatrics Childhood tumors 9efce15d

Chromosome involved in Wilm's tumor is

A
11
B
13
C
18
D
22
High-Yield Explanation
WTl is the best characterized Wilms tumor gene. It is located at chromosome llp13 and encodes for a transcription factor that is critical for normal development of kidneys and gonads. WT2 is localized to a cluster of genes at llpl5. Reference: Essential paediatrics; O.P.Ghai; Childhood Malignancies; Page no: 617

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