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Gynaecology & Obstetrics General 9ee989fd

Congenital heart disease is most likely in the newborn of mothers suffering from all except:

A
Systemic lupus erythematosus
B
Rheumatoid arthritis
C
Diabetes in pregnancy,
D
Congenital heart disease of the mother
High-Yield Explanation
Lets analyse each option separately “Fetal congenital cardiac disease is increased by 3–10% if either of the parents have congenital heart lessons.” Dutta 7/e, p 276. (so option d is correct) “Neonatal lupus syndrome is due to crossing of maternal lupus antibodies (anti-Ro or anti-La) to the fetus causing hemolytic anemia, leukopenia and thrombocytopenia. Isolated congenital heart block is present in about one-third of cases. An apparently healthy woman delivering a baby with congenital heart block should be observed for the development of SLE.” Dutta 7/e, p 293 (i.e. option a is correct) Matenal diabetes we all know leads to fetal heart disease (Dutta 7/e, p 284), so our answer by exclusion is rheumatoid arthritis.

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