Physiology All India exam 9ee515a6 Which of the following is the mechanism of action of Fondaparinux? A Factor Xa inhibition and Thrombin inhibition B Factor Xa inhibition C Antithrombin inhibitor D Thrombin inhibition High-Yield Explanation The antithrombotic activity of fondaparinux sodium is the result of antithrombin III (ATIII) mediated selective inhibition of Factor Xa.