A nurse has been found to be seropositive for both HbsAg and HbeAg. She is suffering from:(AIIMS November 2014, May 2013)

Ans. a. Acute infectious hepatitis B (Ref: Harrison 19/e, 2005, 18/e p2550)Patients who are seropositive for both HbsAg and HbeAg are suffering from acute infectious hepatitis B. (AllMS May 2013 Repeat) HBs AgAnti-Hbs AbAnti-Hbc AbHBe AgAnti-Hbe AbHBV DNAAcute Hepatitis B (early)+--+-+Acute Hepatitis B (high infectivity)+-IgM+-+/-Acute Hepatitis B (recovery)++IgG-+-Chronic Hepatitis B, high replication+-IgG+-+Chronic Hepatitis B, low replication+-IgG-+-Chronic Hepatitis B, pre-core mutant+-IgG-++Chronic Hepatitis B, inactive carrier+-IgG +/-Low level +Chronic Hepatitis B, reactivation+-IgM+-+Hepatitis B Vaccine-+----